Recently, the research team of Chen Qing'an, research group of biomimetic catalytic synthesis Innovation Zone (group 02t4) of Dalian Institute of Chemical Physics, Chinese Academy of Sciences, has made new progress in the regulation of hydrosilylation selectivity of isoprene, and has developed a "ligand regulation" strategy, which can obtain two regional selectivity.

Isoprene is a common industrial chemical, and its hydrosilation reaction can quickly produce high-value organosilicon compounds. However, due to the small difference in electrical properties of the four carbon atoms of isoprene, it is difficult to control the hydrosilation regioselectivity. Therefore, it is urgent to develop a universal strategy to accurately control the regioselectivity of isoprene hydrosilation.

Chen Qingan’s team has been committed to the regioselective regulation of isoprene (Angew. Chem. Int. Ed. 2019, 58, 5438; Chem. Sci. 2019, 10, 9560; Chin. J. Catal. 2020, 41, 1401 ). Based on the previous "metal-hydrogen" regulation, the team has recently developed a novel "ligand regulation" strategy: using cheap divalent iron as the active catalyst center, focusing on regulating its coordination environment as the core idea, respectively Tridentate and bidentate pyridineimine ligands were designed. They found that the tridentate ligands can promote the hydrosilation reaction at the 3 and 4 positions of isoprene to obtain homoallyl silicon compounds; while the bidentate ligands can change the regioselectivity to 4,1-addition. , Get allyl silicon compound. This work has a good reference for changing the selectivity by adjusting the metal coordination environment.

Relevant research results were published in "Angew. Chem. Int. Ed.". The above work was funded by the National Natural Science Foundation of China and the Xingliao Talents Program. (Text/Picture by Gui Changsheng)

Source: http://www.dicp.ac.cn/xwdt/kyjz/202008/t20200827_5677652.html

Disclaimer: This article is translated by cpolymer. The translation is for reference only. All contents are subject to the original text.